Neuropsychological Dysfunction among HIV Infected Drug Abusers

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Neuropsychological Dysfunction among HIV Infected Drug Abusers.

Human immunodeficiency virus (HIV) has been documented to cause direct and indirect central nervous system dysfunction that can be observed as a progressive decline in neuropsychological functioning in a large proportion of persons with HIV and AIDS. Neuropsychological decline in individuals with HIV is characterized by cognitive and motor slowing, attentional deficits, executive dysfunction an...

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Longitudinal neuropsychological evaluation of HIV-infected intravenous drug users.

The present study aimed to describe the cognitive status of a group of HIV-positive asymptomatic intravenous drug users (IVDU) and changes which occurred over a 12-month follow-up period. Forty-two HIV positive IVDU were selected and matched for age, sex, educational level and pattern of drug abuse with 39 seronegative IVDU controls. Baseline and follow-up evaluation included neuropsychological...

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Unnatural deaths among drug abusers.

BACKGROUND Deaths caused by drug abuse, in which the cause of death is intoxication, so-called overdose deaths, are regularly reported and studied. Other deaths related to drug abuse have been less frequently studied. We wished to investigate the prevalence and characteristics of unnatural deaths in persons in whom drugs were detected in blood samples taken at autopsy. MATERIAL AND METHOD A t...

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New Antiretroviral Therapies and Potential Drug Interactions in HIV-Infected Drug Abusers

Substance abuse remains a major obstacle in treating HIV-infected patients. The high prevalence of drug use is responsible for lack of adherence and severe drug interactions to antiretroviral therapy in HIV positive individuals. Over the past decade, newer therapies for HIV have been developed by targeting different stages of HIV life cycle. Of importance, targeting initial binding with recepto...

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Osteoarticular infection in intravenous drug abusers: influence of HIV infection and differences with non drug abusers.

OBJECTIVES To determine (a) the influence of HIV in developing osteoarticular infections in intravenous drug abusers (IVDAs) and (b) the differences between the clinical features of osteoarticular infections in IVDAs and a control group of non-IVDAs. METHODS A comparative study of the clinical features of osteoarticular infections in all HIV positive and HIV negative IVDAs admitted to the dep...

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ژورنال

عنوان ژورنال: American Journal of Infectious Diseases

سال: 2006

ISSN: 1553-6203

DOI: 10.3844/ajidsp.2006.67.73